100 µg (lyophilized)
Reactive oxygen species (ROS) are involved in oxidation of lipids (lipid peroxidation) and lipid membranes are one of the major targets of ROS. Lipid peroxidation results in formation of a variety of aldehydes. Among them, 4-hydroxy-2-nonenal (4-HNE) is an alpha, beta unsatulated aldehyde that can be formed by peroxidation of omega-6 unsatulated fatty acids such as linoleic acid and arachidonic acid. In-vivo 4-HNE is reported to originate from phospholipid-bound arachidonic acid. 4-HNE is considered to be one of the most reliable biomarkers of lipid peroxidation.