DNA base pairs can be damaged by reactive oxygen species. Cells have systems in place to excise damaged bases which results in the production and subsequent excretion of the damaged portion of DNA.
One such system, OGG1 acts to remove oxidized guanine in the form of 8-hydroxydeoxyguanosine (8OHDG). Other byproducts of oxidative stress, specifically malondialdehyde due to lipid peroxidation can react with oxidized guanine to form MDA-8OHDG, another biomarker of oxidative mediated damage to DNA.
|Urinary 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit||NWK-8OHDG01||$945.00 each|
|High Sensitivity 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Assay Kit||NWK-8OHDG02||$945.00 each|
|8-Hydroxydeoxyguanosine (8OHDG) Antibody: Clone 15A3 (100 µg)||NWA-8OHdG||$395.00 each|
|8-Hydroxydeoxyguanosine (8-OHDG) Antibody: Clone N45.1 (20 µg)||NWA-MOG020||$495.00 each|
|8-Hydroxydeoxyguanosine (8-OHDG) Antibody: Clone N45.1 (100 µg)||NWA-MOG100||$1,595.00 each|
Northwest Life Science offers a range of laboratory services. If you prefer to send your samples out for testing, we can help.
Let us help! Give our specialists a call (or contact us online) and let us help you figure out the best biomarker for your needs. We love discussing research!
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