Anti Mn SOD (SOD2) Polyclonal Antibody

NWLSS | Northwest Life Science Specialties, LLC.
NWA-SOD2P021 $375.00 each

For questions & ordering, call:
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Introduction

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. Among them, Mn SOD is a manganese containing 80 kDa tetrameric enzyme. SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain (3).


Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant human protein purified from E.coli
Cross Reactivity
Human, Mouse, Rat
Application(s): Western blotting (1:2000)
Immunoprecipitation (1ul/400ul lysates)
Storage/Stability:
Stable for 2 years at -20 °C
Packaging Size:
100 μL
Format:
Liquid
Concentration:
0.25 mg/mL

References:
1) Kuninaka, S. et al. (2000) Br. J. Cancer. 83, 928-934. 
2) Strange, R. W. et al. (2003) J. Mol. Biol. 328, 877-891. 
3) Weisiger, R. A., and Fridovich, I. (1973) J. Biol. Chem. 248, 3582-3592. 
4) Enghild, J. J. et al. (1999) Biochem J. 317, 51-57.

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