Introduction
Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. Among them, Cu/Zn SOD, also known as cytosolic SOD or SOD1, is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Copper and Zinc ion per subunit (2).
| Host: |
Mouse |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Immunogen: |
Recombinant human protein purified from E.coli |
Cross Reactivity
|
Human |
| Application(s): |
Immunoprecipitation (1-2ul/400ul lysates) |
Storage/Stability:
|
Stable for 2 years at -20 °C |
Packaging Size:
|
100 μL |
Format:
|
Liquid |
Concentration:
|
1 mg/mL |
|
References:
1) Kuninaka, S. et al. (2000) Br. J. Cancer. 83, 928-934.
2) Strange, R. W. et al. (2003) J. Mol. Biol. 328,877-891.
3) Weisiger, R. A., and Fridovich, I. (1973) J. Biol. chem. 248, 3582-3592.
4) Enghild, J. J. et al. (1999) Biochem J. 317, 51-57..
